Capsiplex Burn Review

Burn By Capsiplex Ingredients

100mg Capsimax - Capsimax is a patented blend of capsaicinoids, which are bioactive compounds found in chili peppers (Capsicum annuum). The predominant capsaicinoids in Capsimax are capsaicin, dihydrocapsaicin, and nordihydrocapsaicin. Capsaicinoids are known to elicit a sensation of heat and spiciness in the oral cavity and gastrointestinal tract when consumed. 100mg is within the realms of the effective range, but this is in a lot of other fat burners at this dose, and the patented blend is more for marketing than really much else.

Capsaicinoids have garnered attention in the context of weight management due to their potential effects on metabolism and appetite regulation. Research suggests that capsaicinoids can increase energy expenditure through a process called thermogenesis, whereby excess calories are dissipated as heat. [1] Thermogenesis is primarily mediated by the activation of transient receptor potential vanilloid 1 (TRPV1) receptors located on brown adipose tissue and skeletal muscle. Stimulation of these receptors leads to the release of norepinephrine, which enhances fat oxidation and energy expenditure.

Moreover, capsaicinoids may influence appetite and satiety. [2] Studies have shown that capsaicinoids can suppress appetite, reduce food intake, and increase feelings of fullness. Although there is mixed evidence on this.

250 mg Innoslim - Innoslim is a patented blend of two herbal extracts: Panax ginseng and Astragalus membranaceus. Panax ginseng, commonly referred to as Korean ginseng, contains bioactive compounds known as ginsenosides, which are believed to contribute to its pharmacological effects. Astragalus membranaceus, also known as Huangqi, is an herb commonly used in traditional Chinese medicine. It contains various bioactive components, including flavonoids and polysaccharides.

Innoslim is claimed to exert its effects on weight management through the modulation of mRNA levels, leading to enhanced glucose absorption, fat burning, and increased energy production. However, the precise mechanisms of action of Innoslim and the specific interactions with mRNA remain to be fully elucidated. Limited scientific research is available regarding the weight management effects of Innoslim, and whilst ginseng has been shown to have some impact on body recomposition [3], that’s in larger doses (the full 250mg) so one of the ingredients here isn’t doing much heavy lifting [4]. Realistically it’s probably dosed correctly and it’s the Astragalus that’s just in here for marketing hype. It’s an OK ingredient, and could help with a bit of extra powder in the gym as it’s been shown to increase muscle mass and impact test levels. This is where it’s really helpful for burn by capsiplex.

76mg and 4.5mg Green Tea and Green Coffee Extracts - Green tea extract is derived from the leaves of Camellia sinensis, and green coffee extract is obtained from unroasted coffee beans. Both extracts contain bioactive compounds that have been investigated for their potential contributions to weight management.

Green tea extract is rich in catechins, particularly epigallocatechin gallate (EGCG). Catechins are potent antioxidants and have been suggested to influence weight management through multiple mechanisms. EGCG has been found to increase thermogenesis and fat oxidation, [5] thereby promoting energy expenditure and contributing helping you lose weight. It may also modulate adipocyte metabolism, reduce fat accumulation, and inhibit the activity of enzymes involved in fat digestion and absorption.

Green coffee extract contains chlorogenic acids, which are phenolic compounds with antioxidant properties. Chlorogenic acids have been investigated for their potential effects on glucose metabolism and weight management. They may inhibit glucose absorption [6] in the intestines, reduce hepatic glucose production, and modulate insulin sensitivity. That said, the jury on this is still out and results have been mixed as to whether or not it will actually help you burn fat.

B-Vitamins - B-vitamins, including niacin (B3), pyridoxine (B6), and cobalamin (B12), are essential micronutrients involved in numerous metabolic processes in the body. [7] These vitamins participate in various enzymatic reactions and play critical roles in energy metabolism (burning fat), macronutrient breakdown, and the synthesis of red blood cells.

Niacin, in the form of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), serves as a cofactor for several enzymes involved in cellular metabolism, including those responsible for converting carbohydrates, fats, and proteins into energy. Deficiencies in niacin can impair energy production and overall metabolic function.

Pyridoxine, as pyridoxal phosphate, acts as a cofactor for over 100 enzymes involved in amino acid metabolism, neurotransmitter synthesis, and glycogen breakdown. It plays a crucial role in the metabolism of tryptophan, an amino acid involved in the synthesis of serotonin, a neurotransmitter associated with mood regulation and appetite control.

Cobalamin, commonly known as vitamin B12, is essential for DNA synthesis, red blood cell formation, and the maintenance of neurological function. It is involved in the metabolism of fatty acids and amino acids and plays a crucial role in the conversion of homocysteine to methionine, an essential amino acid. Adequate levels of vitamin B12 are important for maintaining optimal energy production and overall metabolic health. [8]

Iodine - Iodine is an essential trace mineral required for the synthesis of thyroid hormones, thyroxine (T4), and triiodothyronine (T3). These hormones regulate various aspects of metabolism, including basal metabolic rate, thermogenesis, and the utilization of carbohydrates, fats, and proteins for energy production.

Thyroid hormones influence metabolic processes in virtually all cells in the body, affecting oxygen consumption, heat production, and nutrient metabolism. Inadequate iodine intake can lead to impaired thyroid function, resulting in hypothyroidism, which is associated with weight gain, decreased energy expenditure, and difficulties in losing weight. That said, this is only in cases where low iodine is an issue that it’s going to be helpful and it’s not the most common deficiency. [9]

170mcg Chromium - Chromium is a trace mineral that plays a role in glucose metabolism and insulin action. It functions as a cofactor for insulin, facilitating its binding to receptors and enhancing insulin sensitivity. By improving insulin signaling, chromium may contribute to better glucose control and potentially aid in weight management. This is well within the effective dose range and is used in a similar dose across a lot of our top rated fat burners. It’s not the best ingredient in capsiplex, but it takes up relatively little capsule space, making it a good inclusion.

Chromium is involved in the metabolism of macronutrients, particularly carbohydrates and fats. It helps regulate blood sugar levels by enhancing the entry of glucose into cells and promoting its utilization as an energy source. This mechanism may help prevent excessive glucose accumulation and subsequent fat storage.

Additionally, chromium has been suggested to impact appetite regulation. Some studies indicate that chromium supplementation may reduce hunger, cravings for carbohydrates, and binge eating episodes. However, the scientific evidence regarding chromium's effectiveness for weight loss is mixed, and more research is needed to establish its potential benefits and optimal dosages. [10]

800mg L-Tyrosine -  L-Tyrosine is a non-essential amino acid that serves as a precursor for the synthesis of several important neurotransmitters, including dopamine, norepinephrine, and epinephrine. These neurotransmitters play key roles in regulating mood, motivation, and cognitive function.

By influencing neurotransmitter synthesis, L-tyrosine supplementation may support cognitive performance, particularly under conditions of stress, fatigue, or sleep deprivation. It has been suggested to enhance alertness, attention, and working memory, thereby potentially aiding individuals in adhering to dietary and exercise regimens required for weight management.

Furthermore, L-tyrosine is involved in the production of thyroid hormones. Thyroxine (T4) and triiodothyronine (T3) require adequate tyrosine availability for their synthesis. Optimizing thyroid function is essential for maintaining a healthy metabolism and efficient utilization of nutrients. That said, there are far better ingredients than L Tyrosine for craving management, so this is a middle of the road “OK”, but not great inclusion. It should also be mentioned that the studies are relatively mixed on L Tyrosine. [11]

500mg L-Arginine - L-Arginine is a semi-essential amino acid involved in numerous physiological processes. It serves as a precursor for the synthesis of nitric oxide (NO), a molecule involved in the relaxation of blood vessels and the regulation of blood flow. Nitric oxide promotes vasodilation, which may enhance nutrient and oxygen delivery to tissues.

L-Arginine is also known to stimulate the release of growth hormone, insulin, and other substances in the body. Growth hormone plays a role in the regulation of metabolism, body composition, and muscle growth. Insulin is involved in glucose metabolism and nutrient uptake by cells.

Some studies suggest that L-Arginine supplementation may promote lean muscle mass and potentially contribute to fat burning. It is hypothesized that L-Arginine's effects on growth hormone and insulin may play a role in these outcomes. However, further research is required to establish the efficacy and safety of L-Arginine for weight management as it’s not currently very well backed. Again this is another indicator that the Capsiplex Burn supplement is really for people training hard already that are just looking to speed things up a little bit when it comes to weight loss. [12]

20mg Black Pepper (Piperine) - Piperine is a bioactive compound found in black pepper (Piper nigrum) that contributes to its pungent taste and aroma. Piperine has been shown to enhance the bioavailability and absorption of various nutrients and drugs by inhibiting certain enzymes in the liver and intestine. Generally speaking 10mg of this is more than enough to get the desired effects, but it’s not a particularly large amount of capsule space to waste.