Osteo Bi Flex is one of the better over the counter joint supplements available in supermarkets. That's not overly high praise as the vast majority of supplements you can get in Walmart or Walgreens are typically outdated and under dosed. Not all of the Osteo bi flex range is great, though, but there is one product in their range which does stand out as a solid joint pain supplement.
Osteo Bi Flex Triple Strength however is a quite a good collagen supplement, with Osteo bi-flex triple strength containing a high dosage of glucosamine HCL and boswellia, unfortunately the MSM dosage is still a little low to be optimal for a joint supplement, but again it does this better than most that include MSM. So all in all it's not a bad supplement, but there are much better joint pain supplements available at the same price point. And there are some drawbacks to Osteo bi-flex triple strength being a predominantly collagen based joint supplement. And that is that Glucosamine HCL has been shown to reduce joint pain, but isn't as optimal for joint health overall, it's also still not dosed high enough to help much with severe osteoarthritis, even if the dosages do line up with the recommendations for moderate to mild cases. Osteo bi flex is best used in combination with an omega oil supplement for increased efficacy, but is potentially a good option for people who can't have omega 3. It's a decent supplement, it's just a little bit too specialised to be the best joint supplement on the market. It's price point is also a little bit too high for what it is, but it's not a bad option.
As for other osteo bi flex products, there aren't any that we'd recommend. It loses out to FlexAgain as the best overall joint pain supplement, by a long way, but for people who can't have Omega 3 it's pretty good.
That said, due to the high dose of Glucosamine there are a lot of potential interactions for Osteo Bi Flex and it shouldn't be taken by people on, blood thinners, diabetics or people with high blood pressure.
For the most part customers reviews of osteo bi flex triple strength are overwhelmingly positive, there are a few people that do seem to have had adverse effects, but this is always a possibility with higher dosages of glucosamine and MSM.
Typically these complains are around stomach pain and nausea from taking osteo bi flex.
With that in mind osteo bi flex reviews tend towards the more positive side of supplements in general, with a large volume stating it has reduced joint pain significantly, with many specifically referencing knee pain and hip pain. Which does line up with the studies done on said ingredients.
The most commonly asked questions we came across whilst researching our osteo bi flex review.
Osteo bi flex should work to reduce joint pain, with glucosamine actually being a prescription option in some countries the product itself does contain ingredients with enough scientific backing that it's claims are quite reasonable. However, as with all supplements and medications it won't necessarily work for everyone.
Realistically, excluding allergens and specific interactions the most likely side effects of osteo bi flex are going to be nausea. High doses of glucosamine however can cause puffy eyes, and this dosage is not suitable for people with certainly familial conditions, for example it can increase the risk of glaucoma and due to it's effect on blood sugar should be avoided with those on medications for diabetes. It can also effect blood pressure.
You shouldn't take osteo bi flex if you are on blood thinners as glucosamine amplifies the effects.
Osteo Bi Flex gets a lot right in the way of ingredients, although there are a couple of choices that we wouldn't recommend.
Vitamin C is an odd choice for a joint health supplement, with there being multiple options of vitamins which would be better and are in the best joint supplements, vitamin D for example has been shown to reduce joint pain in people who are deficient, and vitamin K is essential for joint health. Vitamin C  however, is a much rarer deficiency that D or K which effect more than half of the US population, and whilst it is essential for joint health could've been replaced with something more useful.
There's a decent amount of evidence that manganese  if combined with glucosamine and chondroitin reduces osteoarthritis pain, and Osteo bi flex contains both of these other ingredients, so this is a much better pick
Sodium is an odd choice, low sodium can cause joint pain, but equally too much sodium can cause inflammation making joint health worse. We really don't like this as an inclusion as the average American diet already contains too much sodium, this is quite a negative for our osteo bi flex review. 
Glucosamine dosed at 1500mg is on the high side for a combined supplement, with 500 mg to 3 grams of glucosamine and chondroitin sulfate being recommended, typically to be taken for at least 1 month to treat joint pain.  Making it pretty much the max recommended dose. Unfortunately this does mean it can have some side effects, but this will be where the main benefits of taking osteo bi flex come from.
Boswellia serrata is a standard amongst the best joint supplements, with it reducing inflammation, it's dosed correctly at 100mg, it's nothing particularly special for a good joint supplement, but a solid inclusion all the same.
The proprietary blend of MSM and Chondroitin sulfate is a little irritating. Because at 1100mg it does mean that both ingredients cannot be ideally dosed, meaning we don't know which is actually going to be in the effective range. We expect that it's Chondroitin as MSM would need to be 99% of this blend to be effective. Which Chondroitin has some use in a joint supplement, it's largely to support the efficacy of glucosamine and doesn't really do much by itself.
Osteo Bi Flex is not bad, taking osteo bi flex will almost certainly help joint pain, if you tolerate the high dose of glucosamine well. The down side is that it's priced at the same point as 2 much better joint supplements. If you're looking for something that's available in your local store however, then it's probably the best that you'll find. It will also be a winner if glucosamine supplements are particularly effective for you. If you do choice to go with Osteo Bi Flex, we recommend taking an omega 3 supplement as well. Not a bad choice, but certainly not the best.
1 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643354/
2 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537775/
3 - https://ods.od.nih.gov/factsheets/Manganese-HealthProfessional/
4 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640209/
5 - https://www.arthritis.org/health-wellness/treatment/complementary-therapies/supplements-and-vitamins/supplement-and-herb-guide-for-arthritis-symptoms