Active Hexose Correlated Compound (AHCC) is an extract derived mostly from shiitake mushrooms. This compound has gained some attention recently for its potential immune boosting properties and its role in various health conditions. That said it's worth noting you can get the same extracts from similar mushrooms however such as lion's mane extract.
What is AHCC?
AHCC is a proprietary extract obtained from the mycelia of shiitake mushrooms (Lentinus edodes). It contains alpha-glucans, polysaccharides, amino acids, lipids, and minerals. The unique combination of these components is believed to contribute to its potential health benefits. There are other compounds that are similar to the standardization and some that do look like they're potentially better in that they're stronger in the effective polysaccharides and alpha glucans that work to boost immunity.
The Science Behind AHCC
Research suggests that AHCC may modulate the immune system by increasing the number and activity of natural killer (NK) cells and T cells. These immune cells play a crucial role in defending the body against infections and cancer.
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Potential Benefits of AHCC
Whilst AHCC has been studied for various health conditions, it's important to note that an awful lot more research is going to be needed to establish just how effective it actually is. Here are some of the potential benefits of AHCC based on the studies we've seen so far:
Immunity - AHCC has shown some quite promising early results in boosting immune function. A small study involving healthy adults found that supplementing with AHCC offset the seasonal dip in immunity that typically occurs during winter. Participants who took AHCC had better immune system function and higher levels of natural killer cells compared to those who took a placebo.
Cancer and AHCC - AHCC has been investigated for its potential role in cancer treatment. Some studies have shown that AHCC can help reduce the side effects of chemotherapy medications and improve the quality of life for people with advanced cancer. For instance, in a study involving pancreatic cancer patients, AHCC supplementation lowered the side effects of gemcitabine, a commonly used chemotherapy drug.
Additionally, AHCC has been studied as an add-on treatment for people with liver cancer who have undergone hepatectomy (partial liver removal). In a small study, AHCC supplementation was associated with a decreased risk of cancer recurrence. There seems to be some of the better evidence when it comes to AHCC and liver health.
Liver Disease - Preliminary research suggests that AHCC may have beneficial effects on liver function. In a clinical trial involving adults with alcohol-related liver disease, AHCC improved liver enzyme levels and reduced markers of inflammation. However, further studies are needed to determine if AHCC can benefit individuals with more severe liver diseases.
Human Papillomavirus (HPV) - AHCC has shown the most promise in the treatment of high-risk HPV infections. There have been more than 30 studies which show that it does seem to be effective. In the most well cited study study involving females with persistent high-risk HPV infections, AHCC supplementation for at least six months effectively treated nearly 60% of the participants, compared to only 10% in the placebo group. It's important to note that AHCC should not be used as a substitute for standard HPV treatment.
Dosage and Safety Considerations
The recommended dosage of AHCC typically ranges from 1 to 3 grams per day, depending on the purpose of use. It's generally considered safe due to the fact that's from shiitake mushrooms, which are of course generally considered safe.
AHCC Conclusion
AHCC does show some early promise in improving the immune system and potentially benefiting a few different conditions. Whilst preliminary research is encouraging it's important to note that it's still very early. If you are considering using AHCC, it is important to consult with a healthcare professional to determine the appropriate dosage and evaluate its suitability for your specific health needs.