Best Nootropic Supplem​ents: Supplements That Boost Brain Function & Help Manage Stress

EASNA review the best nootropic supplements designed to help manage the stress and pressure of the modern world and work environment.

What Are Nootropic Supplements?

Nootropic supplements (often referred to as smart drugs) are a relatively broad category of supplements, it covers pretty much everything that can have a positive impact on your brain function or health. Whether that be immediate focus improvement, memory boosters, sleep aids, stress relievers or even supplements designed to maintain long term eye health. The most popular tend to be nootropics for anxiety, memory and cognitive function allowing people to maintain higher performance at work, as well as maintain improved mental health.

Can Nootropics Really Help To Relieve Anxiety?

Anxiety reduction is one of the most common reasons that people take nootropics aside from improvements to brain function. Generally speaking there is a lot of research backing individual nootropics, but how effective that they're going to be will depend on which nootropics that you are taking. For example, caffeine, is perhaps the most commonly used nootropic, and whilst it does improve focus, with overconsumption it can actually increase anxiety[2].

Nootropic Supplements faq

Some Of The Most Commonly Asked Questions About Nootropics

Do Nootropics Improve Productivity At Work?

Many nootropic supplements improve mental acuity, they also improve brain energy, allowing people to maintain high performance for prolonged periods of time. On average the longest a person can focus on a creative task is around 90 minutes, then breaks are required. With average brain function continuing for up to 6 hours. In theory nootropics can help people retain focus on creative tasks for 30 minutes more and increase overall function to 10-12 hours.  

Are Nootropic Supplements Safe?

Natural nootropic supplements are generally contain ingredients that are considered completely safe for human consumption, that doesn't mean that you can't take too much, but in general there shouldn't be any issues unless you suffer from specific allergies. There are sometimes side effects such as an upset stomach and if you experience any issues you should stop taking them and speak to your physician. All of the nootropics and smart drugs on our best nootropic supplements list are produced in FDA approved factories.

Do Nootropic Supplements Work?

The short answer is yes, the long answer is that how effective they are will differ from person to person and what you're using them for.

What Is The Best Nootropic Supplement?

We rate the best nootropics overall as Hunter Focus, but this is a generalised nootropic designed to cover all basses whether that's to boost brain function, improve focus or improve anxiety.

The Best Nootropic For Focus And Overall - Hunter Focus

Hunter Focus is quite possibly the king of brain supplements on the market right now, containing almost every ingredient on our top ingredients list, it is the highest dosed nootropic on our list. Scoring highly in all categories, memory retention, cognitive function, mood, stress and focus it's no surprise it tops our list. It is a premium nootropic, but it is the most highly dosed of all the brain supplements on this list. Generally speaking it does become a lot more affordable when purchased in bulk, but that does mean committing to taking it for a few months. The manufacturer does offer a money back satisfaction guarantee which does mitigate some concern. That means no matter how you're looking to improve brain function it's got you covered. The only real drawback is that the serving size is a bit high. 

We generally recommend Hunter Focus for anyone looking for a catch all nootropic supplement. Our personal experience was that it notably improved cognitive functions, and it's our go to nootropic of choice. It contains the highest (and optimal) dosage of Bacopa, as well as Ginseng and Ahwaganda not contained in the other nootropic supplements on this list, making it the most effective for mood regulation. The fact it contains caffeine does mean it is more effective for focus as well, however, as some people that have high caffeine sensitivity may want to avoid Hunter even though the dosage is not particularly high. You can purchase it from

Why We Rate Hunter Focus As The Best Nootropic Supplements

Hunter Focus is a premium nootropic which actually earns it's price tag. None of the ingredients are under dosed unlike a lot of cheaper options which simply include ingredients that do improve brain function, but not in an high enough volume to actually be effective. The Hunter range doesn't just include nootropic supplements mind, and their pedigree is consistent across all their products with full dosing being a consistent focus for the brand. They also offer a 90 day money back guarantee, so they're one of the lowest risk options on the market. We've already mentioned that they manage to cover more bases than the competitors, making them the most complete pre made nootropic stack on the list, making them great for fist time nootropic users looking to improve cognitive function and brain health. In comparison to the other supplements on this list, they include Ashwagandha, Ginseng and Spanish Sage. It's also the highest dosed in terms of L-Tyrosine and Citicoline making it the most effective in terms of improving brain energy and clearing brain fog.

What's In Hunter Focus Nootropics?

As you can see in the image, pretty much everything you could ask for in a nootropic stack. It will be quicker to talk about what isn't in it. It is missing Alpha GPC and Reversatrol, but that's about it. These particular ingredients are however mostly useful for long term brain health and people with specific attention related disorders, over the average person. Whilst we'd have liked to see Alpha GPC, Hunter focus really doesn't have any space for more ingredients, the serving size is already the largest on our list by a long way. The star ingredient is Citicoline which is in all the best nootropics due to it's proven cognitive benefits and the high dosage easily makes up for the lack of Alpha. Hunter really is the best of the best when it comes to nootropic supplements, and we can't recommend it highly enough.

Highly Dosed 
Covers All Nootropic Areas
Money Back Guarantee
Contains Ingredients Missed By A Lot Of Other Smart Drugs

Highest Price Point
Only Available From Hunter Store
Contains Caffeine Which Could Put People Off

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Category Score
Focus 10/10
Memory 9.5/10
Stress 10/10
Mood 10/10
Brain Health 10/10
Value 9.5/10
Overall 10/10


1 - - Mental well-being at the workplace

2 - - Caffeine Intake and Mental Health in College Students

3 - - Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial

4 - - Association of Use of Omega-3 Polyunsaturated Fatty Acids With Changes in Severity of Anxiety Symptoms

5 - - Bioavailability and conversion of plant based sources of omega-3 fatty acids - a scoping review to update supplementation options for vegetarians and vegans

6 - - Vitamin D supplementation improves anxiety but not depression symptoms in patients with vitamin D deficiency

7 - - Prevalence and correlates of vitamin D deficiency in US adults

8 - - Therapeutic Potential of Hericium erinaceus for Depressive Disorder

9 - - Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake

10 - - Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease

11 - - Neuronal Health – Can Culinary and Medicinal Mushrooms Help?

12 - - Piracetam improves cognitive performance by restoring neurochemical deficits

13 - - Piracetam: A Review of Pharmacological Properties and Clinical Uses
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15 - S-phenylpiracetam, a selective DAT inhibitor, reduces body weight gain without influencing locomotor activity

16 - - Neuroprotective and anti-inflammatory activity of DAT inhibitor R-phenylpiracetam in experimental models of inflammation

17 - - Phosphatidylserine and the human brain

18 - - Comparison of the effects of acetyl L-carnitine and amantadine for the treatment of fatigue in multiple sclerosis: results of a pilot, randomised, double-blind, crossover trial

19 - - Evaluation of the effects of pycnogenol (French maritime pine bark extract) supplementation on inflammatory biomarkers and nutritional and clinical status in traumatic brain injury patients in an intensive care unit: A randomized clinical trial protocol

20 - - Caffeine: Cognitive and Physical Performance Enhancer

21 - - Nicotine and Behavior in Adult ADHD

22 - - Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia

23 - - Metabolic Agents that Enhance ATP can Improve Cognitive Functioning: A Review of the Evidence for Glucose, Oxygen, Pyruvate, Creatine, and L-Carnitine

24 - - Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial.

25 - - Creatine supplementation and cognitive performance in elderly individuals

26 - - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults

27 - - Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions

28 - - L-Tyrosine to alleviate the effects of stress?

29 - - S-Adenosylmethionine (SAMe) for Neuropsychiatric Disorders: A Clinician-Oriented Review of Research